Sulfamethoxazole/trimethoprim: 7 things you should know
Sulfamethoxazole and trimethoprim is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia. Sulfamethoxazole and trimethoprim may also be used for purposes not listed in this medication zi255.com names: Bactrim DS, Cotrim, Septra DS, Septra, SMZ-TMP DS. Feb 05, · Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet; Suspension.
Medically reviewed by Carmen Fookes, BPharm. Last updated on Nov 9, If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:. Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects.
The risk of side effects may be higher in the elderly. An interaction between two medications it is no secret what god can do lyrics not always mean sulfaethoxazole you must stop taking one of the medications; however, sometimes it does.
Speak to your doctor about how drug interactions should be managed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Sulfamethoxazole stops bacteria from making dihydrofolic acid and trimethoprim prevents the formation of tetrahydrofolic acid; both significant steps in the formation of nucleic acids and proteins essential to many bacteria.
The sulfamethoxazole component belongs to the class of medicines known as sulfonamides, and the trimethoprim component belongs to the class of medicines known as folic acid inhibitors.
Active against a wide range of susceptible strains of gram-positive and gram-negative bacteria, such as Streptococcus pneumoniaeKs coliKlebsiella species, Enterobacter species, Haemophilus influenzaeand others. Effective concentrations of both sulfamethoxazole and trimethoprim are reached in the gastrointestinal tract, urinary tract, lungs, mouth, middle ear, and vagina. Both antibiotics also cross the placenta and are excreted in human milk. Bacterial resistance is less likely to develop with the how to make std calls from cisco ip phone of sulfamethoxazole and trimethoprim than if either ingredient sulfamethoxazole or trimethoprim is taken alone.
Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Nausea, vomiting, abdominal pain, diarrhea, mouth or tongue inflammation, weight loss, flatulence, rash, and itchy skin. May not whqt suitable for some people including those with kidney or liver disease, folate deficiency the elderly, chronic alcoholics, and people taking anticonvulsants are at risk of folate deficiencyglucosephosphate deficiency, porphyria, severe allergies, thyroid dysfunction, or bronchial asthma.
Not suitable for pregnant or breastfeeding women or sulfamethoxazolf infants less than two months of age. Reactions have included Stevens-Johnson syndrome a disorder involving the skin and mucous membranesliver disease, and blood disorders such as thrombocytopenia low platelets.
May lower blood sugar levels in people without diabetes. May interact with a number of other drugs including thiazides, warfarin, phenytoin, methotrexate, digoxin, and medications for diabetes. View complete list spinning wheel how to make side effects 4. Tips May be trimethoprimm with or without food. Swallow tablets with a big glass of water. Discontinue and seek urgent medical advice if a skin rash develops.
Complete the full course as prescribed unless instructed not to do so by your doctor to reduce the risk of resistant bacteria developing. Should not be used in pregnant or lactating women or in babies less than two months old. Seek urgent medical advice if an unexplained cough, shortness of breath, sore throat, fever, muscle or joint pain, paleness or yellowing of the skin, or diarrhea develop. Contact your doctor if diarrhea develops either during tfimethoprim or within a couple of months of ending treatment.
Keep well hydrated with fluids to avoid the development of crystals in the urine or kidney stones. Drug Status Availability Prescription only Rx. Akorn, Inc. Drug Class. Related Drugs. Subscribe to our newsletters. FDA Safety Alerts for all medications.
1. How it works
Dec 01, · Sulfamethoxazole and Trimethoprim is a synthetic antibacterial combination product available in DS (double strength) tablets, each containing mg sulfamethoxazole, USP and mg trimethoprim, USP; in tablets, each containing mg sulfamethoxazole, USP and 80 mg trimethoprim, USP for oral administration.
Medically reviewed by Drugs. Written by Cerner Multum. Sulfamethoxazole and trimethoprim is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea , shigellosis , and Pneumocystis jiroveci pneumonia.
Sulfamethoxazole and trimethoprim may also be used for purposes not listed in this medication guide. You should not use sulfamethoxazole and trimethoprim if you have severe liver disease , kidney disease that is not being monitored, anemia caused by folic acid deficiency, if you take dofetilide , or if you have had low platelets caused by using trimethoprim or a sulfa drug.
You should not use this medicine if you are allergic to sulfamethoxazole or trimethoprim, or if you have:. Sulfamethoxazole and trimethoprim may harm an unborn baby or cause birth defects. Tell your doctor if you are pregnancy or if you become pregnant. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Shake the oral suspension liquid before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon.
A healthcare provider will give the first injection and may teach you how to properly use the medication by yourself. When using injections by yourself, be sure you understand how to properly mix and store the medicine.
Ask your doctor or pharmacist if you don't understand all instructions. Drink plenty of fluids to prevent kidney stones while you are using this medicine. Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.
This medicine will not treat a viral infection such as the flu or a common cold. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using sulfamethoxazole and trimethoprim. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.
Do not use two doses at one time. Overdose symptoms may include loss of appetite, vomiting , fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.
Antibiotic medicines can cause diarrhea , which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. If you use the injection form of sulfamethoxazole and trimethoprim, do not eat or drink anything that contains propylene glycol an ingredient in many processed foods, soft drinks, and medicines.
Dangerous effects could occur. Sulfamethoxazole and trimethoprim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors.
Get emergency medical help if you have signs of an allergic reaction hives , cough, chest pain, shortness of breath, swelling in your face or throat or a severe skin reaction fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body.
Symptoms may include: skin rash, fever, swollen glands, joint pain, muscle aches, severe weakness, pale skin, unusual bruising, or yellowing of your skin or eyes. This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. You may need more frequent check- ups or medical tests if you also use medicine to treat depression , diabetes, seizures , or HIV. Tell your doctor about all your current medicines. Many drugs can affect sulfamethoxazole and trimethoprim, especially:. This list is not complete and many other drugs may affect sulfamethoxazole and trimethoprim. This includes prescription and over-the-counter medicines, vitamins , and herbal products.
Not all possible drug interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Sulfamethoxazole and trimethoprim. Drug Status Availability Prescription only Rx. Akorn, Inc. Drug Class. Related Drugs. Subscribe to our newsletters. FDA Safety Alerts for all medications. Daily MedNews.